Description

4-trans-Phenylcyclohexane-(1R,2-Cis)-Dicarboxylic Imide is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its rigid, functionalized structure makes it a valuable precursor for the development of novel pharmaceuticals, agrochemicals, and specialty materials. This compound is particularly sought after by research and development chemists in the pharmaceutical industry for creating enantiomerically pure active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides, where specific stereochemistry is crucial for bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: A building block for advanced polymers and liquid crystals, contributing to thermal stability and specific optical properties.
• Academic & Contract Research: Essential for methodological studies in organic chemistry and for contract research organizations (CROs) serving the life sciences sector.

Basic Information

Item	Detail
Product Name	4-trans-Phenylcyclohexane-(1R,2-Cis)-Dicarboxylic Imide
CAS No.	336185-25-2
Molecular Formula	C14H15NO2
Molecular Weight	229.28 g/mol
Synonyms	(1R,2S)-rel-4-(Phenylcyclohexane)-1,2-dicarboximide; (1R,2S)-4-trans-Phenylcyclohexane-1,2-dicarboxylic acid imide; 4-trans-Phenyl-1,2-cyclohexanedicarboximide (1R,2S isomer); (1R,2S)-4-Phenylcyclohexane-1,2-dicarboximide; 4-Phenylcyclohexane-cis-1,2-dicarboxylic imide (1R,2S); Chiral Cyclohexane Imide Derivative
EINECS	Contact for details

Quality Control

Every batch of 4-trans-Phenylcyclohexane-(1R,2-Cis)-Dicarboxylic Imide is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and identification is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.