Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 3-[[(Phenylmethoxy)Carbonyl]Amino]-, (1R,2S,3R,4S)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures with precise three-dimensional control, which is critical for developing active pharmaceutical ingredients (APIs) and specialty materials. It is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors focused on asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel drug candidates, particularly in areas requiring rigid, bicyclic scaffolds.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in enantioselective catalytic reactions.
• Agrochemical Synthesis: Used in the development of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule impacts biological activity.
• Academic & Industrial Research: A valuable tool for chemists exploring new reaction methodologies, total synthesis of natural products, and structure-activity relationship (SAR) studies.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including flavors, fragrances, and advanced polymers with specific chiral properties.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 3-[[(Phenylmethoxy)Carbonyl]Amino]-, (1R,2S,3R,4S)-Rel- (9Ci)
CAS No.	336185-22-9
Molecular Formula	C16H17NO4
Molecular Weight	287.31 g/mol
Synonyms	rel-(1R,2S,3R,4S)-3-[(Benzyloxycarbonyl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid; 3-[(Benzyloxycarbonyl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, rel-(1R,2S,3R,4S)-; N-Cbz-3-aminobicyclo[2.2.1]hept-5-ene-2-carboxylic acid (relative configuration); Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-[[(phenylmethoxy)carbonyl]amino]-, (1R,2S,3R,4S)-rel-; Chiral N-Cbz-protected 3-aminonorbornene carboxylic acid derivative.
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment to guarantee traceability and consistency for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.