Description

2-Thiophenecarbonyl Chloride, 3-Cyano- (9Ci) is a high-value, multi-functional chemical intermediate characterized by its reactive acid chloride group and cyano substituent on the thiophene ring. This compound is essential for the synthesis of complex molecules, enabling the rapid introduction of the 3-cyanothiophene-2-carbonyl moiety into target structures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with tailored biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent for conductive polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed to create sophisticated ligands for metal catalysis and organocatalysts.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D exploring new heterocyclic chemistry and molecular architectures.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring this unique scaffold.

Basic Information

Product Name	2-Thiophenecarbonyl Chloride, 3-Cyano- (9Ci)
CAS No.	335256-23-0
Molecular Formula	C6H2ClNOS
Molecular Weight	171.60 g/mol
Synonyms	3-Cyanothiophene-2-carbonyl chloride; 3-Cyano-2-thenoyl chloride; 2-Thenoyl chloride, 3-cyano-; 3-Cyanothiophene-2-carboxylic acid chloride; 2-Thiophenecarboxylic acid, 3-cyano-, chloride; 3-CN-Thiophene-2-COCl
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarbonyl Chloride, 3-Cyano- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.