Description

Carbamic Acid, n-[2-Amino-4-(2-Thienyl)Phenyl]-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific molecular architecture. This compound is of significant commercial importance for its role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in the development of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of proprietary drug substances and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new chemical entities with potential therapeutic activity.
• Organic Synthesis: Serves as a protected amine precursor in complex organic transformations, leveraging its tert-butyloxycarbonyl (Boc) and thienyl groups.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	Carbamic Acid, n-[2-Amino-4-(2-Thienyl)Phenyl]-, 1,1-Dimethylethyl Ester
CAS No.	335255-43-1
Molecular Formula	C15H18N2O2S
Molecular Weight	290.38 g/mol
Synonyms	tert-Butyl N-[2-Amino-4-(thiophen-2-yl)phenyl]carbamate; 2-Amino-4-(2-thienyl)phenylcarbamic Acid 1,1-Dimethylethyl Ester; Boc-2-Amino-4-(2-thienyl)aniline; N-Boc-2-Amino-4-(2-thienyl)aniline; 4-(Thiophen-2-yl)benzene-1,2-diamine, N-Boc protected; (2-Amino-4-(thiophen-2-yl)phenyl)carbamic acid tert-butyl ester; 335255-43-1
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, n-[2-Amino-4-(2-Thienyl)Phenyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured under controlled conditions suitable for pharmaceutical R&D applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.