Description

2,4'-Dibromoacetophenone-2-13C is a stable isotope-labeled analog of 2,4'-dibromoacetophenone, where the carbon atom at the 2-position of the acetyl group is the carbon-13 isotope. This compound serves as a critical internal standard and tracer in advanced analytical chemistry, enabling precise quantification and metabolic pathway elucidation. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories engaged in method development, pharmacokinetic studies, and environmental analysis using techniques like LC-MS and NMR.

Application

• Internal Standard for Mass Spectrometry (LC-MS/GC-MS): Provides unmatched accuracy in quantitative analysis of its unlabeled counterpart or related metabolites in complex biological and environmental matrices.
• Metabolic Pathway Tracing: Used in pharmaceutical and biochemical research to track the fate of the acetyl moiety in drug metabolism and biological synthesis studies.
• NMR Spectroscopy Studies: The carbon-13 label serves as a powerful probe for structural elucidation and dynamic studies of molecular interactions.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradation products during drug development.
• Environmental Analysis: Enables sensitive detection and accurate measurement of brominated acetophenone derivatives in environmental samples.
• Chemical Synthesis Research: Acts as a labeled building block for synthesizing more complex carbon-13 labeled compounds for research purposes.

Basic Information

Product Name	2,4'-Dibromoacetophenone-2-13C
CAS No.	335081-05-5
Molecular Formula	C8H6Br213CO
Molecular Weight	~279.94 g/mol (for 13C labeled form)
Synonyms	1-(2,4-Dibromophenyl)ethanone-2-13C; 2',4'-Dibromoacetophenone-2-13C; 2,4-Dibromoacetophenone-2-13C; Acetophenone, 2',4'-dibromo-, 2-13C; 13C Labeled 2,4'-Dibromoacetophenone; [2-13C]-2,4'-Dibromoacetophenone; Isotopically Labeled 2,4'-DBA
EINECS	Contact for details

Quality Control

Every batch of 2,4'-Dibromoacetophenone-2-13C is produced and analyzed under strict quality protocols to ensure isotopic and chemical purity for research applications. Our quality commitment includes verification of isotopic enrichment (typically ≥99 atom % 13C) and chemical purity via advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic purity, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (13C)	≥99 atom %
Chemical Purity (HPLC)	≥98.0%
Melting Point	Specification available upon request
Water Content (KF)	<0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.