Description

(2-Bromo-5-Nitrophenyl)Methanol CAS NO 332883-48-4 is a versatile brominated nitroaromatic building block of significant importance in advanced organic synthesis. Its structure, featuring both an electrophilic bromine atom and a reducible nitro group adjacent to a hydroxymethyl handle, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical R&D departments for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing antimicrobial properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its halogen and nitro functionalities.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings.
• Material Science Research: Acts as a monomer or functionalizing agent in the synthesis of advanced polymers, liquid crystals, or organic electronic materials.
• Dye and Pigment Intermediate: Utilized in the production of specialized azo dyes and nitroaromatic-based colorants.
• Chemical Biology Probes: Functionalized to create molecular probes for studying enzyme activity or cellular processes.

Basic Information

Item	Detail
Product Name	(2-Bromo-5-Nitrophenyl)Methanol
CAS No.	332883-48-4
Molecular Formula	C7H6BrNO3
Molecular Weight	232.03 g/mol
Synonyms	2-Bromo-5-nitrobenzyl alcohol; (2-Bromo-5-nitrophenyl)methanol; 1-(Bromomethyl)-2-nitro-5-bromobenzene; α-(2-Bromo-5-nitrophenyl)methanol; 2-Bromo-5-nitrobenzenemethanol; Benzenemethanol, 2-bromo-5-nitro-; 5-Nitro-2-bromobenzyl alcohol
EINECS	Contact for details

Quality Control

Every batch of (2-Bromo-5-Nitrophenyl)Methanol is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting compliance with cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.