Description

4-[5-(4-Methoxy-Phenyl)-3-Thiophen-2-Yl-4,5-Dihydro-Pyrazol-1-Yl]-4-Oxo-Butyric Acid is a high-purity, non-racemic chiral building block and advanced pharmaceutical intermediate. This compound matters for its precise molecular architecture, which is critical in the research and development of novel therapeutic agents targeting specific biological pathways. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing complex molecules for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential drug candidates, particularly in medicinal chemistry programs.
• Chemical Biology Research: Used as a molecular scaffold or probe in studying enzyme inhibition and receptor-ligand interactions.
• Process Development: Serves as a critical reference standard and starting material for scaling up synthetic routes under GMP or non-GMP conditions.
• Academic Research: Employed in university and institutional labs for methodological studies in heterocyclic and asymmetric synthesis.
• Custom Synthesis: A foundational component for the contract manufacturing of specialized, high-value fine chemicals and APIs.

Basic Information

Item	Detail
Product Name	4-[5-(4-Methoxy-Phenyl)-3-Thiophen-2-Yl-4,5-Dihydro-Pyrazol-1-Yl]-4-Oxo-Butyric Acid
CAS No.	332390-97-3
Molecular Formula	C20H20N2O4S
Molecular Weight	384.45 g/mol
Synonyms	4-Oxo-4-[5-(4-methoxyphenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]butanoic acid; 4-[5-(4-Methoxyphenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazol-1-yl]-4-oxobutanoic acid; 332390-97-3; Butanoic acid, 4-[5-(4-methoxyphenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazol-1-yl]-4-oxo-; 4-(5-(4-Methoxyphenyl)-3-(thiophen-2-yl)-4,5-dihydropyrazol-1-yl)-4-oxobutanoic acid
EINECS	Contact for details

Quality Control

Our 4-[5-(4-Methoxy-Phenyl)-3-Thiophen-2-Yl-4,5-Dihydro-Pyrazol-1-Yl]-4-Oxo-Butyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and impurity profiling, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.