Description

2-(3,3-Dimethyl-3,4-Dihydro-Isoquinolin-1-Yl-Methylsulfanyl)-Benzoic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and other therapeutic areas. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and novel chemical entities (NCEs).
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial building block in multi-step synthetic routes for target APIs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis.
• Biochemical Research: Employed in academic and industrial research to study biological pathways and develop new therapeutic agents.
• Process Chemistry & Scale-Up: Utilized in the development and optimization of scalable, GMP-compliant manufacturing processes.

Basic Information

Product Name	2-(3,3-Dimethyl-3,4-Dihydro-Isoquinolin-1-Yl-Methylsulfanyl)-Benzoic Acid
CAS No.	332358-90-4
Molecular Formula	C19H19NO2S
Molecular Weight	325.42 g/mol
Synonyms	2-[(3,3-Dimethyl-3,4-dihydro-1H-isoquinolin-1-yl)methylsulfanyl]benzoic acid; 2-((3,3-Dimethyl-3,4-dihydroisoquinolin-1(2H)-yl)methylthio)benzoic acid; Benzoic acid, 2-[[(3,3-dimethyl-3,4-dihydro-1H-isoquinolin-1-yl)methyl]thio]-; 332358-90-4; 1,2,3,4-Tetrahydro-3,3-dimethyl-1-[[(2-carboxyphenyl)thio]methyl]isoquinoline
EINECS	Contact for details

Quality Control

Our 2-(3,3-Dimethyl-3,4-Dihydro-Isoquinolin-1-Yl-Methylsulfanyl)-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.