Description

2-(6,7-Dimethoxy-3,3-Dimethyl-3,4-Dihydro-Isoquinolin-1-Ylmethylsulfanyl)-Benzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic benzoic acid structure. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular pathways. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to ensure the integrity and efficacy of their final drug products.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel therapeutic agents, especially for central nervous system (CNS) and cardiovascular drug candidates.
• Organic Synthesis Building Block: Used in research and development for constructing complex heterocyclic frameworks and introducing specific functional groups.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals requiring precise molecular architecture.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP-compliant API production.
• Academic & Industrial R&D: Utilized in laboratories for exploratory chemistry and process development for new chemical entities (NCEs).

Basic Information

Product Name	2-(6,7-Dimethoxy-3,3-Dimethyl-3,4-Dihydro-Isoquinolin-1-Ylmethylsulfanyl)-Benzoic Acid
CAS No.	332358-89-1
Molecular Formula	C21H23NO4S
Molecular Weight	385.48 g/mol
Synonyms	2-[(6,7-Dimethoxy-3,3-dimethyl-3,4-dihydro-1-isoquinolinyl)methylthio]benzoic acid; Benzoic acid, 2-[[(3,4-dihydro-6,7-dimethoxy-3,3-dimethyl-1-isoquinolinyl)methyl]thio]-; 2-({[6,7-Dimethoxy-3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-yl]methyl}sulfanyl)benzoic acid; 332358-89-1; Isoquinoline-benzoic acid derivative; Dihydroisoquinoline thioether intermediate
EINECS	Contact for details

Quality Control

Our 2-(6,7-Dimethoxy-3,3-Dimethyl-3,4-Dihydro-Isoquinolin-1-Ylmethylsulfanyl)-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for pharmaceutical R&D and cGMP applications. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.