Description

(S)-3-Amino-4-(2-thienyl)-butyric acid hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its value lies in its role as a key synthon for the synthesis of complex bioactive molecules, particularly in the development of novel therapeutics. This compound is essential for research and production in the pharmaceutical, biotechnology, and fine chemical industries, where precise stereochemistry is critical for biological activity.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder drugs.
• Peptide Mimetics & Drug Discovery: Used to incorporate a thienyl-substituted γ-amino acid moiety into peptide backbones, modifying stability and receptor binding properties.
• Asymmetric Synthesis: Serves as a starting material or chiral auxiliary in asymmetric catalytic processes to construct complex molecular architectures.
• Bioconjugation & Probe Development: Utilized in the creation of labeled compounds and molecular probes for biochemical and diagnostic research.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and process development in academic and industrial R&D laboratories.

Basic Information

Product Name	(S)-3-Amino-4-(2-thienyl)-butyric acid hydrochloride
CAS No.	332061-90-2
Molecular Formula	C8H12ClNO2S
Molecular Weight	221.70 g/mol
Synonyms	(S)-3-Amino-4-(2-thienyl)butanoic acid hydrochloride; (S)-3-Amino-4-(thiophen-2-yl)butyric acid HCl; (3S)-3-Amino-4-(2-thienyl)butanoic acid hydrochloride; (S)-AABA(2-Thienyl)-HCl; (S)-γ-Amino-β-(2-thienyl)-butyric acid hydrochloride; (S)-H-Aaba(2-Thienyl)-OH·HCl; L-3-Amino-4-(2-thienyl)butyric acid hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-4-(2-thienyl)-butyric acid hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.