Description

5-Amino-3-Methyl-N~2~-Phenylthiophene-2,4-Dicarboxamide is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both amino and dicarboxamide functionalities on a thiophene core, makes it a versatile precursor for constructing complex pharmacophores and specialty materials. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a core structure in the research and production of new-generation herbicides, fungicides, and plant growth regulators.
• Material Science Research: Used in the synthesis of organic semiconductors, conductive polymers, and advanced dyes due to its electron-rich thiophene backbone.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes, enzyme inhibitors, and tagged compounds for biological studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	5-Amino-3-Methyl-N~2~-Phenylthiophene-2,4-Dicarboxamide
CAS No.	331959-40-1
Molecular Formula	C13H13N3O2S
Molecular Weight	275.33 g/mol
Synonyms	5-Amino-3-methyl-2,4-bis(phenylcarbamoyl)thiophene; 2,4-Dicarboxamide-5-amino-3-methyl-N~2~-phenylthiophene; 5-Amino-3-methyl-N2-phenylthiophene-2,4-dicarboxamide; AM-PTDA; Thiophene-2,4-dicarboxamide, 5-amino-3-methyl-N~2~-phenyl-; 331959-40-1
EINECS	Contact for details

Quality Control

Every batch of 5-Amino-3-Methyl-N~2~-Phenylthiophene-2,4-Dicarboxamide is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets exacting specifications suitable for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.