Description

(R)-3-Amino-4-(3-Benzothienyl)-Butyric Acid-Hcl CAS NO 331847-10-0 is a high-purity chiral intermediate featuring a benzothiophene moiety and a γ-aminobutyric acid (GABA) backbone. This compound is of significant value for its role as a key building block in the synthesis of novel, optically active pharmaceuticals and bioactive molecules. It is primarily required by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) drugs, enzyme inhibitors, and other therapeutic agents where stereochemical purity is critical.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in neurology and psychiatry.
• Protease Inhibitor Synthesis: Used in the construction of peptide mimetics and inhibitors targeting specific enzymes.
• Chemical Biology Research: Serves as a valuable probe or precursor in studying receptor-ligand interactions and signal transduction pathways.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to create complex chiral molecules.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(R)-3-Amino-4-(3-Benzothienyl)-Butyric Acid Hydrochloride
CAS No.	331847-10-0
Molecular Formula	C₁₂H₁₄ClNO₂S
Molecular Weight	271.76 g/mol
Synonyms	(R)-3-Amino-4-(3-benzothienyl)butanoic acid hydrochloride; (R)-3-Amino-4-(benzo[b]thiophen-3-yl)butyric acid HCl; (3R)-3-Amino-4-(1-benzothiophen-3-yl)butanoic acid hydrochloride; GABA benzothiophene derivative; (R)-3-AABA-Benzothienyl-HCl; 331847-10-0; (R)-ATBA-HCl
EINECS	Contact for details

Quality Control

Our (R)-3-Amino-4-(3-Benzothienyl)-Butyric Acid-Hcl is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.