Description

8-Bromo-6-Chloro-3-Cyano-4-Methylcoumarin is a highly functionalized coumarin derivative that serves as a critical advanced intermediate in organic synthesis. Its value lies in its unique halogenated and nitrile-substituted structure, enabling the construction of complex molecules for high-value applications. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research targeting various therapeutic areas.
• Agrochemical Research: Used in developing new pesticides, herbicides, and fungicides due to its bioactive coumarin core and halogen substituents.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials or emissive layer dopants in electronic device manufacturing.
• Fluorescent Dye & Probe Synthesis: Utilized to create specialized coumarin-based fluorescent tags and sensors for biochemical and diagnostic applications.
• Material Science: Intermediate for synthesizing advanced polymers and organic frameworks with specific optical or electronic properties.
• Academic & Industrial R&D: Essential reagent for methodological studies in synthetic organic chemistry and process development.

Basic Information

Product Name	8-Bromo-6-Chloro-3-Cyano-4-Methylcoumarin
CAS No.	331821-06-8
Molecular Formula	C12H5BrClNO2
Molecular Weight	310.53 g/mol
Synonyms	8-Bromo-6-chloro-4-methyl-2-oxo-2H-chromene-3-carbonitrile; 6-Chloro-8-bromo-4-methylcoumarin-3-carbonitrile; 2H-1-Benzopyran-3-carbonitrile, 8-bromo-6-chloro-4-methyl-2-oxo-; 331821-06-8; 8-Bromo-6-chloro-4-methyl-2-oxo-2H-1-benzopyran-3-carbonitrile; 8-Bromo-6-chloro-3-cyano-4-methyl-2H-chromen-2-one
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Chloro-3-Cyano-4-Methylcoumarin is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.