Description

Ethyl 2-(4-Nitrobenzamido)-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxylate is a high-purity synthetic organic intermediate characterized by its fused thiophene and cycloheptane ring system. This compound matters as a critical building block in advanced pharmaceutical research and development, enabling the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecular entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory pathways, or as kinase inhibitors.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides, fungicides, or insecticides with unique modes of action.
• Chemical Biology Probe Development: Used to create tool compounds for studying biological pathways and protein functions in academic and industrial research settings.
• Material Science Applications: Potential intermediate for synthesizing organic semiconductors or advanced polymers due to its conjugated thiophene moiety.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise molecular architecture.

Basic Information

Product Name	Ethyl 2-(4-Nitrobenzamido)-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxylate
CAS No.	331819-60-4
Molecular Formula	C21H22N2O5S
Molecular Weight	414.48 g/mol
Synonyms	Ethyl 2-[(4-nitrobenzoyl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate; 2-(4-Nitrobenzamido)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic Acid Ethyl Ester; 4H-Cyclohepta[b]thiophene-3-carboxylic acid, 2-[(4-nitrobenzoyl)amino]-5,6,7,8-tetrahydro-, ethyl ester; Ethyl 2-(4-nitrobenzamido)-4,5,6,7-tetrahydrocyclohepta[b]thiophene-3-carboxylate; CAS 331819-60-4
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Nitrobenzamido)-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical characteristics are provided and available upon request. We support development and commercial projects with material produced to meet cGMP standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.