Description

4-Chloro-8-Fluoro-5H-Pyrimido[5,4-B]Indole is a high-purity, advanced pharmaceutical intermediate belonging to a class of fused heterocyclic compounds. This compound matters for its critical role as a key building block in the synthesis of novel, targeted therapeutic agents, particularly in oncology and antiviral research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to develop next-generation small molecule drugs, where its specific halogenated indole-pyrimidine structure enables crucial molecular interactions.

Application

• Pharmaceutical Intermediate: Primary use as a core scaffold in the research and development of new active pharmaceutical ingredients (APIs).
• Oncology Drug Discovery: Serves as a key precursor for kinase inhibitors and other targeted cancer therapies due to its fused heterocyclic structure.
• Antiviral Agent Synthesis: Utilized in the synthetic pathways for developing compounds with potential antiviral activity.
• Biochemical Research: Acts as a specialized reagent in proteomics and molecular biology studies for probing enzyme function.
• Agrochemical Intermediate: Potential application in the synthesis of advanced, high-performance crop protection agents.
• Material Science Research: Investigated for use in creating organic electronic materials and photoactive compounds.

Basic Information

Item	Detail
Product Name	4-Chloro-8-Fluoro-5H-Pyrimido[5,4-B]Indole
CAS No.	331443-96-0
Molecular Formula	C10H5ClFN3
Molecular Weight	221.62 g/mol
Synonyms	4-Chloro-8-fluoro-5H-pyrimido[5,4-b]indole; 5H-Pyrimido[5,4-b]indole, 4-chloro-8-fluoro-; 331443-96-0; 4-Chloro-8-fluoropyrimido[5,4-b]indole; 8-Fluoro-4-chloro-5H-pyrimido[5,4-b]indole; 4-Chloro-8-fluoro-5H-pyrimido[5,4-b]indole (CAS 331443-96-0); 4-Chloro-8-fluoro-5H-pyrimido[5,4-b]indole, 95%
EINECS	Contact for details

Quality Control

Our 4-Chloro-8-Fluoro-5H-Pyrimido[5,4-B]Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.