Description

2-Amino-n-(2-Methoxyphenyl)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of proprietary drug candidates and novel chemical entities.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: A key building block for constructing complex molecular architectures found in potential therapeutic agents.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Chemical Biology: Employed in the development of chemical probes for target validation and biological pathway analysis.

Basic Information

Product Name	2-Amino-n-(2-Methoxyphenyl)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxamide
CAS No.	330188-63-1
Molecular Formula	C15H16N2O2S
Molecular Weight	288.36 g/mol
Synonyms	2-Amino-N-(2-methoxyphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide; 2-Amino-N-(2-methoxyphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide; 4H-Cyclopenta[b]thiophene-3-carboxamide, 2-amino-N-(2-methoxyphenyl)-5,6-dihydro-; 330188-63-1; 2-Amino-N-(2-methoxyphenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide; Tetrahydrobenzothiophene carboxamide derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-n-(2-Methoxyphenyl)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxamide is produced and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.