Description

(1S)-2-Chloro-1-(2,4-Difluorophenyl)Ethanol is a high-purity chiral intermediate of significant importance in modern synthetic chemistry. Its value lies in its role as a key building block for the synthesis of complex, biologically active molecules, particularly in the pharmaceutical sector. This compound is essential for research and development chemists and manufacturers in the agrochemical and pharmaceutical industries who require enantiomerically pure intermediates for producing advanced active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of antifungal, antibacterial, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for efficacy.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new catalytic processes.
• Fine Chemical Manufacturing: Employed in custom synthesis and the production of specialty chemicals requiring a defined stereocenter.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(1S)-2-Chloro-1-(2,4-Difluorophenyl)Ethanol
CAS No.	330156-49-5
Molecular Formula	C8H7ClF2O
Molecular Weight	192.59 g/mol
Synonyms	(S)-2-Chloro-1-(2,4-difluorophenyl)ethanol; (1S)-2-Chloro-1-(2,4-difluorophenyl)ethan-1-ol; (-)-2-Chloro-1-(2,4-difluorophenyl)ethanol; (S)-(-)-2-Chloro-1-(2,4-difluorophenyl)ethanol; 2-Chloro-1-(2,4-difluorophenyl)-(S)-ethanol; 1-(2,4-Difluorophenyl)-2-chloro-(1S)-ethanol; (S)-1-(2,4-Difluorophenyl)-2-chloroethanol
EINECS	Contact for details

Quality Control

Our (1S)-2-Chloro-1-(2,4-Difluorophenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.