Description

(2-Benzenesulfonyl-1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Acetic Acid CAS NO 329905-83-1 is a specialized organic compound featuring a tetrahydroisoquinoline core functionalized with a benzenesulfonyl group and an acetic acid moiety. This unique molecular architecture makes it a valuable pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological or cardiovascular pathways.
• Medicinal Chemistry Research: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Synthesis Building Block: Used in the construction of complex heterocyclic compounds due to its reactive functional groups.
• Process Development: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for studying organic reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	(2-Benzenesulfonyl-1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Acetic Acid
CAS No.	329905-83-1
Molecular Formula	C₁₇H₁₇NO₄S
Molecular Weight	331.39 g/mol
Synonyms	2-(2-Benzenesulfonyl-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid; 1,2,3,4-Tetrahydro-2-(phenylsulfonyl)-1-isoquinolineacetic acid; 2-[(2-Phenylsulfonyl-3,4-dihydro-1H-isoquinolin-1-yl)]acetic acid; 2-(2-(Phenylsulfonyl)-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid; 2-(2-Benzenesulfonyl-3,4-dihydro-1H-isoquinolin-1-yl)acetic acid; (2-(Phenylsulfonyl)-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to verify identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing batch-specific results. Our quality management system is designed to support GMP-grade applications and research requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.