Description

5-(Piperidin-1-Ylsulfonyl)-1H-Indole-2,3-Dione is a high-purity, synthetic organic compound belonging to the class of isatin sulfonamide derivatives. This specialized chemical serves as a critical pharmaceutical intermediate and research-grade building block for medicinal chemistry and drug discovery programs. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Probe Development: Serves as a core structure for developing selective inhibitors to study biological pathways and validate new therapeutic targets.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to create complex heterocyclic molecules due to its reactive isatin and sulfonamide functional groups.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental research in organic chemistry and pharmacology.

Basic Information

Product Name	5-(Piperidin-1-Ylsulfonyl)-1H-Indole-2,3-Dione
CAS No.	329905-79-5
Molecular Formula	C13H14N2O4S
Molecular Weight	294.33 g/mol
Synonyms	5-(1-Piperidinosulfonyl)isatin; 5-(Piperidin-1-ylsulfonyl)isatin; 1H-Indole-2,3-dione, 5-(1-piperidinylsulfonyl)-; 5-Piperidin-1-ylsulfonyl-1H-indole-2,3-dione; 5-(Piperidine-1-sulfonyl)isatin; 5-(N-Piperidinosulfonyl)isatin; Isatin-5-piperidinyl sulfone; CAS 329905-79-5
EINECS	Contact for details

Quality Control

Our 5-(Piperidin-1-Ylsulfonyl)-1H-Indole-2,3-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the stringent requirements for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.