Description

Benzenemethanol, α-(Chloromethyl)-3-Nitro-, (Alphar)- (9Ci) is a specialized nitro-aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate, enabling the construction of complex molecules with precise stereochemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates requiring specific stereocenters.
• Agrochemical Synthesis: Used in the preparation of advanced, high-value crop protection agents and herbicides where the nitro and chloromethyl functionalities are leveraged.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for producing specialty chemicals with complex aromatic backbones.
• Academic and Industrial Research: A valuable tool in methodological chemistry research for studying nitro group transformations and nucleophilic substitution reactions.

Basic Information

Product Name	Benzenemethanol, α-(Chloromethyl)-3-Nitro-, (Alphar)- (9Ci)
CAS No.	329348-23-4
Molecular Formula	C8H8ClNO3
Molecular Weight	201.61 g/mol
Synonyms	(αR)-α-(Chloromethyl)-3-nitrobenzenemethanol; (R)-(-)-α-(Chloromethyl)-3-nitrobenzyl Alcohol; (R)-2-Chloro-1-(3-nitrophenyl)ethanol; (R)-3-Nitro-α-(chloromethyl)benzyl Alcohol; α-(Chloromethyl)-3-nitrobenzenemethanol, (αR)-; (R)-Nitrochloromethylbenzyl Alcohol; (R)-C3NCMB Alcohol; (R)-enantiomer of 2-Chloro-1-(3-nitrophenyl)ethanol
EINECS	Contact for details

Quality Control

Our production of Benzenemethanol, α-(Chloromethyl)-3-Nitro-, (Alphar)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to meet the exacting standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.