Description

Dimethyl 2-[({[4-(1-Methylethyl)Phenyl]Oxy}Acetyl)Amino]-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3,4-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting specific biological pathways. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially in therapeutic areas requiring complex molecular architectures.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions for clinical trial material production.
• Fine Chemical Synthesis: Employed in the custom synthesis of specialized, high-value compounds for research and development purposes.
• Reference Standard: Can be supplied as a certified reference material for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	Dimethyl 2-[({[4-(1-Methylethyl)Phenyl]Oxy}Acetyl)Amino]-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3,4-Dicarboxylate
CAS No.	329223-86-1
Molecular Formula	C24H27NO6S
Molecular Weight	457.54 g/mol
Synonyms	Dimethyl 2-({2-[4-(1-Methylethyl)phenoxy]acetamido}-5,6-dihydro-4H-cyclopenta[b]thiophene-3,4-dicarboxylate; 2-({2-[4-(Propan-2-yl)phenoxy]acetamido}-4,5,6,7-tetrahydro-1-benzothiophene-3,4-dicarboxylic acid dimethyl ester; 3,4-Dicarbomethoxy-2-({2-[4-(isopropyl)phenoxy]acetamido}-4,5,6,7-tetrahydrobenzo[b]thiophene; CAS 329223-86-1; Advanced Thiophene Intermediate; Isopropylphenoxy Acetamide Thiophene Derivative
EINECS	Contact for details

Quality Control

Our Dimethyl 2-[({[4-(1-Methylethyl)Phenyl]Oxy}Acetyl)Amino]-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3,4-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.