Description

(S)-Tulobuterol CAS NO 329183-10-0 is a high-purity, single-enantiomer form of the β-2 adrenergic receptor agonist tulobuterol. This specific stereoisomer is of significant interest due to its enhanced pharmacological activity and selectivity compared to the racemic mixture. It serves as a critical chiral intermediate and reference standard in advanced pharmaceutical research and development. Key industries that require this compound include pharmaceutical manufacturing, contract research organizations (CROs), and academic institutions focused on respiratory therapeutics and chiral chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel bronchodilators and respiratory medications.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control (QC) of tulobuterol-based drug products.
• Pharmacological Research: Employed in preclinical studies to investigate the specific mechanisms, efficacy, and safety profile of the (S)-enantiomer.
• Chiral Catalyst & Ligand Development: Acts as a precursor or model compound in the design and testing of asymmetric synthesis catalysts.
• Metabolite Studies: Utilized in ADME (Absorption, Distribution, Metabolism, and Excretion) research to identify and characterize metabolic pathways.

Basic Information

Product Name	(S)-Tulobuterol
CAS No.	329183-10-0
Molecular Formula	C12H18ClNO
Molecular Weight	227.73 g/mol
Synonyms	(S)-2-(tert-Butylamino)-1-(2-chlorophenyl)ethanol; (S)-1-(2-Chlorophenyl)-2-(tert-butylamino)ethanol; (-)-Tulobuterol; (S)-Tulobuterol Hydrochloride (salt form); Tulobuterol S-Enantiomer; (S)-C-78; (S)-Form of β2-Adrenoceptor Agonist
EINECS	Contact for details

Quality Control

Our (S)-Tulobuterol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with a detailed Certificate of Analysis (COA), which includes results from chiral purity analysis (HPLC), assay, and related substance tests. Specifications are designed to meet the stringent requirements of pharmaceutical R&D and reference standard applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (S)-enantiomer
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.