Description

2-(3-Carboxy-Propionylamino)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought after by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in the development of new chemical entities and proprietary drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules, especially those targeting specific enzyme pathways.
• Organic Synthesis Building Block: Utilized in research and development for constructing novel heterocyclic compounds containing fused cyclopentane and thiophene rings.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of potential drug candidates.
• Custom Synthesis: Supplied for contract manufacturing and development projects requiring high-purity, specialized intermediates.
• Chemical Reference Standard: Used as a certified reference material for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	2-(3-Carboxy-Propionylamino)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxylic Acid Methyl Ester
CAS No.	328025-47-4
Molecular Formula	C14H17NO5S
Molecular Weight	311.35 g/mol
Synonyms	Methyl 2-[(3-carboxypropanoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate; 2-[(3-Carboxypropanoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid methyl ester; 5,6-Dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid, 2-[(3-carboxy-1-oxopropyl)amino]-, methyl ester; CAS 328025-47-4
EINECS	Contact for details

Quality Control

Our 2-(3-Carboxy-Propionylamino)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.