Description

2-({[3-(Methoxycarbonyl)-5,6-Dihydro-4H-Cyclopenta[B]Thien-2-Yl]Amino}Carbonyl)Benzoic Acid is a high-purity, non-racemic organic compound featuring a complex fused-ring structure, making it a valuable advanced pharmaceutical intermediate and key building block for sophisticated chemical synthesis. Its molecular architecture is specifically engineered for constructing active pharmaceutical ingredients (APIs) and other high-value specialty chemicals. This product is essential for research institutions and manufacturers in the pharmaceutical and fine chemical sectors requiring precise, high-quality intermediates for complex molecular assembly.

Application

This specialized intermediate is designed for advanced chemical synthesis, primarily serving the following applications:

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Active Pharmaceutical Ingredient (API) Development: Serves as a key chiral building block in the research and production of enantiomerically pure APIs, where its specific stereochemistry is crucial for biological activity.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic compounds, leveraging its cyclopentathiophene and benzoic acid functionalities.
• Ligand and Catalyst Synthesis: Employed in the development of novel chiral ligands or organocatalysts for asymmetric synthesis applications.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors or advanced polymeric materials due to its conjugated system potential.

Basic Information

Item	Details
Product Name	2-({[3-(Methoxycarbonyl)-5,6-Dihydro-4H-Cyclopenta[B]Thien-2-Yl]Amino}Carbonyl)Benzoic Acid
CAS No.	328024-25-5
Molecular Formula	C17H15NO5S
Molecular Weight	345.37 g/mol
Synonyms	2-[[(3-Methoxycarbonyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)carbamoyl]benzoic acid; 2-({[3-(Methoxycarbonyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]amino}carbonyl)benzoic acid; 2-[(3-Carbomethoxy-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)carbamoyl]benzoic acid; Methyl 2-[(2-carboxybenzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; CAS 328024-25-5
EINECS	Contact for details

Quality Control

Our production of 2-({[3-(Methoxycarbonyl)-5,6-Dihydro-4H-Cyclopenta[B]Thien-2-Yl]Amino}Carbonyl)Benzoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical parameters such as assay, chiral purity, and impurity profiles. Our quality system is designed to meet the exacting standards required for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.