Description

6,7-Dimethoxy-2-Methylsulfonyl-3,4-Dihydro-1H-Isoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its distinct heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex molecular scaffolds due to its reactive methylsulfonyl and dihydroisoquinoline groups.
• Research & Development (R&D): Essential for academic and industrial R&D labs exploring new chemical entities and structure-activity relationships (SAR).
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of target APIs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	6,7-Dimethoxy-2-Methylsulfonyl-3,4-Dihydro-1H-Isoquinoline
CAS No.	328022-71-5
Molecular Formula	C₁₂H₁₅NO₄S
Molecular Weight	269.32 g/mol
Synonyms	2-Methylsulfonyl-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline; 6,7-Dimethoxy-2-(methylsulfonyl)-1,2,3,4-tetrahydroisoquinoline; 3,4-Dihydro-6,7-dimethoxy-2-(methylsulfonyl)-1H-isoquinoline; 2-Methanesulfonyl-6,7-dimethoxy-3,4-dihydroisoquinoline; 6,7-Dimethoxy-2-methanesulfonyl-1,2,3,4-tetrahydroisoquinoline; CAS 328022-71-5
EINECS	Contact for details

Quality Control

Our 6,7-Dimethoxy-2-Methylsulfonyl-3,4-Dihydro-1H-Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.