Description

1,2-Dipalmitoyl-D62-Sn-Glycero-3-[Phospho-L-Serine] (Sodium Salt) is a deuterated phospholipid, specifically a perdeuterated dipalmitoyl phosphatidylserine sodium salt. This compound is of critical importance for advanced biophysical and biochemical research, offering a stable, non-radioactive isotopic label for probing membrane structure, dynamics, and protein-lipid interactions. It is primarily needed by research institutions, pharmaceutical R&D departments, and specialty chemical manufacturers focused on lipidomics, membrane biophysics, and drug delivery system development.

Application

• Membrane Biophysics Research: As a deuterated analog, it is essential for neutron scattering and solid-state NMR studies to investigate lipid bilayer structure, phase behavior, and dynamics without interfering with the system's natural properties.
• Biomimetic Model Systems: Used to create defined, isotopically-labeled liposomes and supported lipid bilayers (SLBs) for studying protein-membrane interactions and cell signaling mechanisms.
• Drug Delivery Vehicle Development: Serves as a key component in the formulation of targeted liposomal carriers, where phosphatidylserine can play a role in specific cellular uptake mechanisms.
• Metabolic Tracing & Lipidomics: The deuterium labeling allows for precise tracking and quantification of phosphatidylserine metabolism and turnover in complex biological systems using mass spectrometry.
• Apoptosis & Cell Signaling Studies: Used in research models to study the role of externalized phosphatidylserine in apoptosis (programmed cell death) and related immune responses.
• Reference Standard: Acts as a high-purity analytical standard for the identification and quantification of phosphatidylserine species in commercial or biological samples.

Basic Information

Product Name	1,2-Dipalmitoyl-D62-Sn-Glycero-3-[Phospho-L-Serine] (Sodium Salt)
CAS No.	327178-94-9
Molecular Formula	C41D62NNaO10P
Molecular Weight	~809.4 g/mol (Calculated for deuterated form)
Synonyms	DPPS-d62 (Sodium Salt); 1,2-Dihexadecanoyl-D62-sn-glycero-3-phospho-L-serine (Sodium Salt); Perdeuterated Dipalmitoylphosphatidylserine; Deuterated DPPS; Phosphatidylserine-d62 (DPPS, Na salt); L-α-Phosphatidylserine-d62 (DPPS); 1,2-Dipalmitoyl-sn-glycero-3-phosphoserine-d62 (Sodium Salt); PS-d62 (16:0/16:0).
EINECS	Contact for details

Quality Control

Our deuterated phospholipids are produced and handled under strict quality protocols to ensure isotopic purity and chemical integrity. Each batch is characterized using a combination of advanced analytical techniques, including NMR for deuterium incorporation and HPLC for chemical purity. Certificates of Analysis (COA) are provided, detailing specifications for isotopic enrichment (typically >98 atom % D), chemical purity (by HPLC), and identity confirmation. We support research requiring traceable and consistent material quality.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (NMR)	Conforms to structure
Isotopic Purity (Atom % D)	>98% (by 2H NMR or MS)
Chemical Purity (HPLC)	>95% (Area %)
Assay	>90% (by phosphorus analysis)
Solubility	Soluble in chloroform, methanol mixtures; forms vesicles in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.