Description

1-Stearoyl-D35-2-Hydroxy-Sn-Glycero-3-Pc is a high-purity, deuterated phospholipid derivative, specifically a phosphatidylcholine analog with a perdeuterated stearoyl chain. This compound is critical for advanced research applications where isotopic labeling is required to enhance analytical sensitivity and trace metabolic pathways without interference. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and analytical chemistry sectors for sophisticated studies in lipidomics, membrane biophysics, and drug delivery systems.

Application

• Biophysical Research: As a deuterated probe for studying lipid bilayer structure, dynamics, and phase behavior using techniques like NMR spectroscopy and neutron scattering.
• Metabolic Tracing: Employed in stable isotope labeling experiments (SIL) to track the incorporation and turnover of phospholipids in cellular and in vivo systems.
• Analytical Standards: Serves as an internal standard for the precise quantification of native phosphatidylcholines in complex biological matrices via mass spectrometry (LC-MS, GC-MS).
• Pharmaceutical Development: Used in the formulation and study of advanced liposomal and lipid nanoparticle (LNP) drug delivery systems to investigate stability and biodistribution.
• Membrane Protein Studies: Facilitates the reconstitution and functional analysis of membrane proteins within a defined, isotopically labeled lipid environment.

Basic Information

Product Name	1-Stearoyl-D35-2-Hydroxy-Sn-Glycero-3-Pc
CAS No.	327178-92-7
Molecular Formula	C44H78D35NO9P
Molecular Weight	Contact for details
Synonyms	1-Stearoyl(d35)-2-hydroxy-sn-glycero-3-phosphocholine; Deuterated Lyso-PC (18:0-d35); 1-Octadecanoyl-d35-2-hydroxy-sn-glycero-3-phosphocholine; Lyso-PC-d35 (18:0); 1-Stearoyl-2-hydroxy-sn-glycero-3-phosphocholine-d35; L-α-Lysophosphatidylcholine-d35 (stearoyl); Deuterated Lysophosphatidylcholine; 1-(Octadecanoyl-d35)-2-hydroxy-sn-glycero-3-phosphocholine
EINECS	Contact for details

Quality Control

Our 1-Stearoyl-D35-2-Hydroxy-Sn-Glycero-3-Pc is manufactured under strict quality systems to ensure the highest standards of isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR and mass spectrometry to confirm deuterium incorporation and chemical purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, isotopic enrichment, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment (MS)	≥ 98 atom % D
Chemical Purity (TLC)	Single spot
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.