Description

(E)-3-(3-((3,4-Dihydroisoquinolin-2(1H)-yl)sulfonyl)-4-methoxyphenyl)acrylic acid is a high-purity, synthetically derived organic compound featuring a unique molecular scaffold that combines an acrylic acid moiety with a dihydroisoquinoline sulfonamide structure. This compound is valued as a critical pharmaceutical intermediate and a versatile research chemical for medicinal chemistry programs. It is primarily sought by R&D and production teams in the pharmaceutical, biotechnology, and fine chemical sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those targeting enzyme inhibition or receptor modulation.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Biochemical Probe Development: Utilized in the design and creation of molecular probes for studying biological pathways and target validation.
• Fine Chemical Synthesis: Acts as a specialized intermediate for the custom synthesis of complex, high-value organic molecules for various industrial applications.
• Academic Research: Employed in university and institutional labs for advanced organic synthesis projects and methodological development.

Basic Information

Product Name	(E)-3-(3-((3,4-Dihydroisoquinolin-2(1H)-yl)sulfonyl)-4-methoxyphenyl)acrylic Acid
CAS No.	327094-27-9
Molecular Formula	C19H17NO5S
Molecular Weight	371.41 g/mol
Synonyms	(E)-3-[3-(3,4-Dihydro-1H-isoquinoline-2-sulfonyl)-4-methoxyphenyl]acrylic acid; 2-Propenoic acid, 3-[3-(3,4-dihydro-1H-isoquinolin-2-ylsulfonyl)-4-methoxyphenyl]-, (E)-; (E)-3-(3-(3,4-Dihydroisoquinoline-2(1H)-sulfonyl)-4-methoxyphenyl)acrylic acid; 327094-27-9; (E)-3-(3-(1,2,3,4-Tetrahydroisoquinoline-2-sulfonyl)-4-methoxyphenyl)acrylic acid; (E)-3-(4-Methoxy-3-((1,2,3,4-tetrahydroisoquinolin-2-yl)sulfonyl)phenyl)acrylic acid; Acrylic acid derivative CAS 327094-27-9
EINECS	Contact for details

Quality Control

Our production of (E)-3-(3-((3,4-Dihydroisoquinolin-2(1H)-yl)sulfonyl)-4-methoxyphenyl)acrylic acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against comprehensive specifications using advanced analytical techniques including HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.