Description

Ethyl 4-{[4-(2,3-Dihydro-1H-Indol-1-Ylsulfonyl)Phenyl]Amino}-4-Oxobutanoate is a high-purity, advanced pharmaceutical intermediate characterized by its specific indole-sulfonamide molecular architecture. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of proprietary drug candidates, especially those with indole-based scaffolds.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Research: Potential use as a tool compound or inhibitor in enzymatic and receptor-binding assays.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Ethyl 4-{[4-(2,3-Dihydro-1H-Indol-1-Ylsulfonyl)Phenyl]Amino}-4-Oxobutanoate
CAS No.	327070-60-0
Molecular Formula	C20H20N2O5S
Molecular Weight	400.45 g/mol
Synonyms	Ethyl 4-((4-(2,3-Dihydro-1H-indole-1-sulfonyl)phenyl)amino)-4-oxobutanoate; 4-{[4-(2,3-Dihydro-1H-indol-1-ylsulfonyl)phenyl]amino}-4-oxobutanoic acid ethyl ester; Butanoic acid, 4-[[4-(2,3-dihydro-1H-indol-1-ylsulfonyl)phenyl]amino]-4-oxo-, ethyl ester; Ethyl 4-oxo-4-({4-[(2,3-dihydro-1H-indol-1-yl)sulfonyl]phenyl}amino)butanoate; 1-[4-(Ethoxycarbonyl)butanoyl]amino-4-(2,3-dihydroindol-1-ylsulfonyl)benzene; CAS 327070-60-0
EINECS	Contact for details

Quality Control

Our Ethyl 4-{[4-(2,3-Dihydro-1H-Indol-1-Ylsulfonyl)Phenyl]Amino}-4-Oxobutanoate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.