Description

5-Acetyl-2-Amino-4-Methyl-3-Thiophenecarbonitrile is a versatile heterocyclic building block featuring a thiophene core substituted with acetyl, amino, methyl, and nitrile functional groups. This compound matters as a critical intermediate in the synthesis of complex organic molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique structure enables the construction of novel active ingredients. It is primarily needed by research chemists and process development scientists working in medicinal chemistry, material science, and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Material Science Research: Serves as a building block for organic semiconductors, conductive polymers, and other functional materials due to its electron-rich thiophene unit.
• Dye and Pigment Manufacturing: Intermediate for creating specialized heterocyclic dyes with specific light-absorption properties.
• Academic & R&D Laboratories: Employed in methodological studies and as a starting material for novel heterocyclic chemistry and scaffold diversification.
• Fine Chemical Production: Used in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	5-Acetyl-2-Amino-4-Methyl-3-Thiophenecarbonitrile
CAS No.	327066-20-6
Molecular Formula	C8H8N2OS
Molecular Weight	180.23 g/mol
Synonyms	2-Amino-5-acetyl-4-methyl-3-thiophenecarbonitrile; 3-Thiophenecarbonitrile, 5-acetyl-2-amino-4-methyl-; 5-Acetyl-2-amino-4-methylthiophene-3-carbonitrile; 4-Methyl-5-acetyl-2-aminothiophene-3-carbonitrile; 2-Amino-4-methyl-5-acetylthiophene-3-carbonitrile; 5-Acetyl-2-amino-4-methyl-3-cyanothiophene
EINECS	Contact for details

Quality Control

Our 5-Acetyl-2-Amino-4-Methyl-3-Thiophenecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.