Description

3-Thiophen-2-Yl-3-(Toluene-4-Sulfonyl)-1-p-Tolyl-Propan-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular structure combining thiophene and sulfonyl moieties. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in process development and scale-up.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, especially those exploring sulfur-containing heterocycles.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs for developing new therapeutic agents.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target APIs.
• Academic Research: Utilized in university and institutional labs for studying organic synthesis methodologies and reaction mechanisms.
• Custom Synthesis: A starting material for the contract manufacturing of specialized fine chemicals and proprietary compounds.

Basic Information

Product Name	3-Thiophen-2-Yl-3-(Toluene-4-Sulfonyl)-1-p-Tolyl-Propan-1-One
CAS No.	327063-44-5
Molecular Formula	C21H20O3S2
Molecular Weight	384.51 g/mol
Synonyms	1-Propanone, 3-(2-thienyl)-3-[(4-methylphenyl)sulfonyl]-1-(4-methylphenyl)-; 3-(Thiophen-2-yl)-3-(p-tolylsulfonyl)-1-(p-tolyl)propan-1-one; 3-(2-Thienyl)-3-[(4-methylphenyl)sulfonyl]-1-(4-methylphenyl)-1-propanone; p-Tolyl 3-(2-thienyl)-3-(p-tolylsulfonyl)propyl ketone; 327063-44-5; Tosyl thiophene propanone derivative
EINECS	Contact for details

Quality Control

Our 3-Thiophen-2-Yl-3-(Toluene-4-Sulfonyl)-1-p-Tolyl-Propan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.