Description

2-((1-(4-(Pyrrolidin-1-Ylsulfonyl)Benzoyl)Piperidin-4-Yl)Methyl)-1H-Benzo[De]Isoquinoline-1,3(2H)-Dione is a sophisticated heterocyclic organic compound featuring a naphthalimide core linked to a piperidine-sulfonyl benzoyl moiety. This complex molecular architecture makes it a valuable advanced pharmaceutical intermediate for research and development in medicinal chemistry. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly those targeting complex biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially for oncology and central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the biological activity and pharmacokinetic properties of lead compounds.
• Biochemical Probe Development: Acts as a core scaffold for developing fluorescent probes or enzyme inhibitors for biological assay development.
• Organic Synthesis Reference Standard: Provides a high-purity standard for analytical method development and validation in chemical process research.
• Academic & Institutional Research: Utilized in university and research institute laboratories for cutting-edge chemical and pharmacological studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client pipelines.

Basic Information

Product Name	2-((1-(4-(Pyrrolidin-1-Ylsulfonyl)Benzoyl)Piperidin-4-Yl)Methyl)-1H-Benzo[De]Isoquinoline-1,3(2H)-Dione
CAS No.	326882-05-7
Molecular Formula	C30H29N3O5S
Molecular Weight	543.64 g/mol
Synonyms	1H-Benzo[de]isoquinoline-1,3(2H)-dione, 2-[[1-[4-(1-pyrrolidinylsulfonyl)benzoyl]-4-piperidinyl]methyl]-; 2-((1-(4-(Pyrrolidine-1-sulfonyl)benzoyl)piperidin-4-yl)methyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione; 4-[(1,3-Dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)methyl]-1-[4-(pyrrolidin-1-ylsulfonyl)benzoyl]piperidine; CAS 326882-05-7; Naphthalimide-piperidine sulfonamide derivative
EINECS	Contact for details

Quality Control

Our production of this high-purity pharmaceutical intermediate adheres to stringent quality protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP starting material requirements. We support custom synthesis to meet specific purity grades and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.