Description

2-(Indolinylsulfonyl)Thiophene is a high-purity, advanced heterocyclic building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its unique molecular architecture, which combines indoline and thiophene moieties linked by a sulfonyl group, making it a versatile synthon in modern organic synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for organic semiconductors, conductive polymers, and advanced functional materials due to the electron-rich thiophene unit.
• Chemical Synthesis: Acts as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Academic & R&D: Employed in university and corporate research laboratories for methodological development and exploration of new chemical spaces.

Basic Information

Item	Detail
Product Name	2-(Indolinylsulfonyl)Thiophene
CAS No.	326881-87-2
Molecular Formula	C12H11NO2S2
Molecular Weight	265.35 g/mol
Synonyms	2-(Indolin-1-ylsulfonyl)thiophene; 1-(Thiophen-2-ylsulfonyl)indoline; Thiophene, 2-[(2,3-dihydro-1H-indol-1-yl)sulfonyl]-; 2-(1-Indolinylsulfonyl)thiophene; 2-(N-Indolinosulfonyl)thiophene; 1-(2-Thienylsulfonyl)indoline
EINECS	Contact for details

Quality Control

Every batch of 2-(Indolinylsulfonyl)Thiophene is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.