Description

Ethanone, 1-[(1R,2S,3R,4S)-3-Mercaptobicyclo[2.2.1]Hept-2-Yl]-, Rel- (9Ci) is a high-purity, stereochemically defined chiral building block featuring a bicyclic norbornane scaffold with a strategically positioned mercapto group and an ethanone moiety. This compound matters for its role as a sophisticated intermediate in the synthesis of complex molecules, where its rigid structure and functional handles enable precise control over three-dimensional architecture. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by specialty chemical manufacturers focused on advanced material science and catalysis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in areas requiring complex, conformationally restricted molecular frameworks.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of functional groups is critical for biological activity.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands used in asymmetric catalysis for fine chemical production.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties derived from its unique bicyclic structure.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme interactions or as a molecular scaffold for probe development due to its thiol functionality.
• Flavor & Fragrance Intermediate: Potential use in the synthesis of high-value, complex aroma chemicals where the norbornane skeleton contributes unique olfactory characteristics.

Basic Information

Item	Details
Product Name	Ethanone, 1-[(1R,2S,3R,4S)-3-Mercaptobicyclo[2.2.1]Hept-2-Yl]-, Rel- (9Ci)
CAS No.	326794-69-8
Molecular Formula	C9H14OS
Molecular Weight	170.27 g/mol
Synonyms	rel-(1R,2S,3R,4S)-3-Mercaptobicyclo[2.2.1]heptan-2-yl ethanone; 1-[(1R,2S,3R,4S)-3-Mercaptobicyclo[2.2.1]hept-2-yl]ethanone; (1R,2S,3R,4S)-2-Acetyl-3-mercaptonorbornane; 3-Mercaptonorbornan-2-yl methyl ketone, rel-; Chiral Norbornane Thiol Ketone; Bicyclo[2.2.1]heptane-2-acetyl-3-thiol; CAS 326794-69-8
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-[(1R,2S,3R,4S)-3-Mercaptobicyclo[2.2.1]Hept-2-Yl]-, Rel- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. The material is characterized and released using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, stereochemical purity, and potency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support compliance with relevant cGMP and ISO 9001 quality management standards for our manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from oxidizing agents and strong bases. Due to its sensitivity, the container should be opened only under an inert atmosphere and resealed immediately after use to minimize oxidation and moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.