Description

Bicyclo[3.1.0]Hexane-1-Carboxaldehyde, 3-Hydroxy-3-Methyl-, (1S,3S,5S)- (9Ci) is a high-purity, stereochemically defined bicyclic aldehyde derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique fused-ring structure and functional groups make it invaluable for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Research: Used in the development of novel, stereoselective pesticides and herbicides where the specific spatial orientation of the molecule is crucial for biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science: Potential monomer or cross-linking agent for creating polymers with unique thermal or mechanical properties derived from its rigid bicyclic core.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process development for stereocontrolled synthetic routes.
• Flavor & Fragrance Intermediate: Can be utilized in the synthesis of high-value odorants and flavoring agents that require specific stereochemistry.

Basic Information

Product Name	Bicyclo[3.1.0]Hexane-1-Carboxaldehyde, 3-Hydroxy-3-Methyl-, (1S,3S,5S)- (9Ci)
CAS No.	326599-87-5
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	(1S,3S,5S)-3-Hydroxy-3-methylbicyclo[3.1.0]hexane-1-carboxaldehyde; (1S,3S,5S)-3-Hydroxy-3-methyl-1-bicyclo[3.1.0]hexanecarboxaldehyde; 3-Hydroxy-3-methylbicyclo[3.1.0]hexane-1-carbaldehyde, (1S,3S,5S)-; Bicyclo[3.1.0]hexane-1-carboxaldehyde, 3-hydroxy-3-methyl-, (1S,3S,5S)-; (1S,3S,5S)-3-Methyl-3-hydroxybicyclo[3.1.0]hexane-1-carbaldehyde; Chiral Bicyclo[3.1.0]hexane Aldehyde Derivative
EINECS	Contact for details

Quality Control

Our production of Bicyclo[3.1.0]Hexane-1-Carboxaldehyde, 3-Hydroxy-3-Methyl-, (1S,3S,5S)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and IR spectroscopy to confirm identity, enantiomeric excess, and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be purged with inert gas after each opening to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.