Description

1,2-Dipalmitoyl-D62-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] (Sodium Salt) is a deuterium-labeled phospholipid, specifically a perdeuterated dipalmitoylphosphatidylglycerol (DPPG-d62) sodium salt. This compound is critically important as a stable, non-radioactive isotopic tracer for advanced biophysical and biochemical research. It is primarily needed by research institutions and pharmaceutical companies engaged in membrane biophysics, lipidomics, drug delivery system development, and metabolic pathway studies using techniques like NMR spectroscopy and mass spectrometry.

Application

• Membrane Biophysics Research: As a deuterated component in model lipid bilayer systems for studying membrane fluidity, phase transitions, and protein-lipid interactions via techniques such as Solid-State NMR and neutron scattering.
• Metabolic Tracing & Lipidomics: Employed as an internal standard or tracer in quantitative mass spectrometry (MS) to investigate phospholipid metabolism, turnover, and trafficking in cellular systems.
• Drug Delivery System Development: Used in the formulation and study of liposomal and nanoparticle-based carriers, where its deuterium label allows for precise tracking of the carrier's fate and stability.
• Pulmonary Surfactant Studies: Acts as a key deuterated analog in research focused on lung surfactant composition, function, and related respiratory pathologies.
• Antimicrobial Mechanism Studies: Incorporated into bacterial model membranes to investigate the interaction mechanisms of antimicrobial peptides and host defense lipids.
• Analytical Reference Standard: Serves as a high-purity certified reference material for the calibration and validation of analytical methods in lipid analysis.

Basic Information

Product Name	1,2-Dipalmitoyl-D62-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] (Sodium Salt)
CAS No.	326495-46-9
Molecular Formula	C41D62NaO10P
Molecular Weight	~794.4 g/mol (for unlabeled form C41H62NaO10P; exact deuterated MW available on request)
Synonyms	DPPG-d62 (Sodium Salt); 1,2-Dihexadecanoyl-D62-sn-glycero-3-phospho-(1'-rac-glycerol) Sodium Salt; Perdeuterated DPPG; Phosphatidylglycerol-d62 (16:0/16:0) Sodium Salt; Deuterated Dipalmitoylphosphatidylglycerol; DPPG-d62, Na salt; 1,2-Dipalmitoyl-d62-sn-glycero-3-phosphoglycerol Sodium Salt; PG(16:0-d62/16:0-d62) Sodium Salt
EINECS	Contact for details

Quality Control

Our deuterated phospholipids are produced and controlled under a strict quality management system to ensure exceptional isotopic purity and chemical integrity. Each batch is characterized by a comprehensive suite of analytical techniques including NMR (¹H, ²H, ³¹P), Mass Spectrometry (MS), and HPLC to confirm identity, isotopic enrichment (typically >98 atom % D), and chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or solid film
Identification (NMR)	Conforms to structure
Isotopic Purity (Atom % D)	≥ 98% (by MS/NMR)
Chemical Purity (HPLC)	≥ 95%
Assay (Phosphorus)	≥ 85% (by weight)
Solubility	Soluble in chloroform, methanol, chloroform/methanol mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.