Description

Benzenemethanol, α-(Chloromethyl)-4-Nitro-, (Alphar)- (9Ci) is a specialized nitro-aromatic benzyl alcohol derivative that serves as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its unique structure, featuring both a reactive chloromethyl group and a nitro substituent, makes it invaluable for constructing complex molecules with high precision. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for applications in drug discovery and the development of high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in constructing nitro-aromatic pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its nitro and chloromethyl functionalities enable specific modes of action.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers and functional materials that require nitro-aromatic monomers.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags in biochemical research.

Basic Information

Product Name	Benzenemethanol, α-(Chloromethyl)-4-Nitro-, (Alphar)- (9Ci)
CAS No.	325856-49-3
Molecular Formula	C8H8ClNO3
Molecular Weight	201.61 g/mol
Synonyms	(αR)-α-(Chloromethyl)-4-nitrobenzenemethanol; (R)-(-)-α-(Chloromethyl)-4-nitrobenzyl Alcohol; (R)-2-Chloro-1-(4-nitrophenyl)ethanol; (R)-1-(4-Nitrophenyl)-2-chloroethanol; 4-Nitro-α-(chloromethyl)benzyl Alcohol, (R)-; (R)-Nitrobenzyl Chlorohydrin Derivative; Alphar-4-Nitrobenzyl Chlorohydrin; NSC 836901
EINECS	Contact for details

Quality Control

Every batch of Benzenemethanol, α-(Chloromethyl)-4-Nitro-, (Alphar)- (9Ci) is produced under strict quality management protocols. We ensure compliance with relevant industry standards for fine chemical intermediates. Our quality assurance includes rigorous analytical testing for identity, purity, and chiral purity (enantiomeric excess). A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and specific rotation is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.