Description

3-(4-Hydroxy-1,1-Dioxo-Tetrahydro-1Lambda6-Thiophen-3-Ylamino)-Propionic Acid is a high-purity, specialized organic intermediate featuring a unique sulfonamide and amino acid-like structure. This compound is valued for its role as a critical building block in advanced pharmaceutical synthesis and fine chemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting sulfonamide-based enzyme inhibitors.
• Agrochemical Research: Used in the development of new herbicides and fungicides that leverage its unique heterocyclic core.
• Bioconjugation & Linker Chemistry: The carboxylic acid and amine functionalities make it suitable for creating peptide mimetics or as a spacer/linker in bioconjugate and prodrug development.
• Material Science Precursor: Serves as a monomer or functionalizing agent for advanced polymers with specific solubility or biological properties.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes for studying enzymatic processes.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	3-(4-Hydroxy-1,1-Dioxo-Tetrahydro-1Lambda6-Thiophen-3-Ylamino)-Propionic Acid
CAS No.	325851-81-8
Molecular Formula	C7H11NO5S
Molecular Weight	221.23 g/mol
Synonyms	3-[(4-Hydroxy-1,1-dioxo-1λ⁶-thiolan-3-yl)amino]propanoic acid; 3-(4-Hydroxy-1,1-dioxotetrahydro-1λ⁶-thiophen-3-ylamino)propionic acid; 4-Hydroxy-tetrahydro-thiophene-1,1-dioxide-3-ylamino-propionic acid; 3-Amino-propionic acid derivative of 4-hydroxy-tetrahydrothiophene 1,1-dioxide; 325851-81-8; (4-Hydroxy-1,1-dioxo-1λ⁶-thiolan-3-yl)-β-alanine
EINECS	Contact for details

Quality Control

Our production of 3-(4-Hydroxy-1,1-Dioxo-Tetrahydro-1Lambda6-Thiophen-3-Ylamino)-Propionic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against established internal specifications, with analytical methods including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.