Description

5-Bromo-3-Formylindole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, multi-functional indole derivative serving as a critical advanced intermediate in modern organic synthesis. Its molecular architecture, featuring both bromo and formyl substituents on the indole core, makes it an exceptionally versatile building block for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical development teams engaged in the creation of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates, particularly for oncology and central nervous system (CNS) targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Material Science: Serves as a monomer or functional unit in the research of organic semiconductors, dyes, and photoresponsive polymers.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the development of enzyme inhibitors.
• Academic & Contract Research: Essential for methodological studies in cross-coupling reactions, palladium-catalyzed transformations, and novel heterocycle formation.

Basic Information

Product Name	5-Bromo-3-Formylindole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	325800-39-3
Molecular Formula	C14H14BrNO3
Molecular Weight	324.17 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-5-bromo-3-formylindole; tert-Butyl 5-bromo-3-formyl-1H-indole-1-carboxylate; 5-Bromo-1-Boc-3-formylindole; 5-Bromo-3-formyl-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 5-Bromoindole-3-carboxaldehyde-1-Boc; Boc-5-Bromo-3-formylindole; 1-Boc-5-bromoindole-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-3-Formylindole-1-Carboxylic Acid tert-Butyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.