Description

Ethyl 2-Amino-4-(2-Chlorophenyl)Thiophene-3-Carboxylate is a high-purity organic building block of significant importance in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and microbial infections.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene core.
• Material Science: Building block for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene structure.
• Chemical Synthesis: Versatile scaffold for further functionalization via reactions at the amino and ester groups, enabling the creation of diverse chemical libraries.
• Academic & R&D: Essential reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	Ethyl 2-Amino-4-(2-Chlorophenyl)Thiophene-3-Carboxylate
CAS No.	325724-66-1
Molecular Formula	C13H12ClNO2S
Molecular Weight	281.76 g/mol
Synonyms	Ethyl 2-Amino-4-(2-chlorophenyl)thiophene-3-carboxylate; 2-Amino-4-(2-chlorophenyl)thiophene-3-carboxylic acid ethyl ester; 4-(2-Chlorophenyl)-2-aminothiophene-3-carboxylic acid ethyl ester; 3-Thiophenecarboxylic acid, 2-amino-4-(2-chlorophenyl)-, ethyl ester; Ethyl α-amino-4-o-chlorophenylthiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-4-(2-Chlorophenyl)Thiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.