Description

Diethyl 3-Methyl-5-(4-(Pyrrolidin-1-Ylsulfonyl)Benzamido)Thiophene-2,4-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific enzymatic pathways. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, especially within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates for various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new molecular entities.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for investigating novel heterocyclic chemistry and reaction methodologies.
• API Synthesis: Integrated into the production chain of complex target molecules requiring a functionalized thiophene dicarboxylate core.

Basic Information

Product Name	Diethyl 3-Methyl-5-(4-(Pyrrolidin-1-Ylsulfonyl)Benzamido)Thiophene-2,4-Dicarboxylate
CAS No.	325694-41-5
Molecular Formula	C22H26N2O7S2
Molecular Weight	494.58 g/mol
Synonyms	Diethyl 3-methyl-5-[[4-(1-pyrrolidinylsulfonyl)benzoyl]amino]-2,4-thiophenedicarboxylate; 2,4-Thiophenedicarboxylic acid, 5-[[[4-(1-pyrrolidinylsulfonyl)phenyl]carbonyl]amino]-3-methyl-, 1,4-diethyl ester; 325694-41-5; 3-Methyl-5-(4-(pyrrolidine-1-sulfonyl)benzamido)thiophene-2,4-dicarboxylic acid diethyl ester
EINECS	Contact for details

Quality Control

Our Diethyl 3-Methyl-5-(4-(Pyrrolidin-1-Ylsulfonyl)Benzamido)Thiophene-2,4-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with the standards expected for pharmaceutical development, supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.