Description

5-Methoxy-3-Formylindole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, multi-functional indole derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a formyl and a protected carboxylic acid group, makes it an indispensable intermediate for constructing complex heterocyclic compounds. This product is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates, including potential kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers and advanced organic electronic materials.
• Academic & Contract Research: Employed in medicinal chemistry programs and as a standard reagent for methodological development in organic synthesis laboratories worldwide.
• Peptidomimetics & Bioconjugation: The reactive aldehyde and protected acid groups allow for its use in constructing peptide analogs and bioconjugation linkers.

Basic Information

Product Name	5-Methoxy-3-Formylindole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	324756-80-1
Molecular Formula	C15H17NO4
Molecular Weight	275.30 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-5-methoxy-3-formylindole; 5-Methoxy-1-Boc-3-formylindole; tert-Butyl 5-methoxy-3-formyl-1H-indole-1-carboxylate; 3-Formyl-5-methoxyindole-1-carboxylic acid tert-butyl ester; 1-Boc-5-methoxyindole-3-carboxaldehyde; 5-Methoxy-3-formyl-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; BOC-5-Methoxy-3-formylindole
EINECS	Contact for details

Quality Control

Our 5-Methoxy-3-Formylindole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.