Description

(4R)-3-[((1S,2S)-2-Hydroxy-3-Cyclopenten-1-Yl)Carbonyl]-4-(Phenylmethyl)-1,3-Oxazolidin-2-One is a high-purity, chiral oxazolidinone derivative that serves as a critical building block and chiral auxiliary in advanced organic synthesis. Its precise stereochemistry makes it invaluable for the enantioselective construction of complex molecules, ensuring high optical purity in the final products. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Employed to induce stereoselectivity in aldol, alkylation, and Diels-Alder reactions.
• Pharmaceutical Intermediate: A key precursor in the research and development of potential therapeutic agents, particularly those requiring specific stereocenters.
• Academic & Process Chemistry Research: Used in methodological studies and scale-up process optimization for complex organic transformations.
• Fine Chemical Synthesis: Integral to the production of specialty chemicals, flavors, and fragrances where enantiopurity is essential.
• Catalyst and Ligand Development: Serves as a scaffold or precursor for novel chiral catalysts and ligands used in homogeneous catalysis.

Basic Information

Product Name	(4R)-3-[((1S,2S)-2-Hydroxy-3-Cyclopenten-1-Yl)Carbonyl]-4-(Phenylmethyl)-1,3-Oxazolidin-2-One
CAS No.	324741-99-3
Molecular Formula	C₁₆H₁₇NO₄
Molecular Weight	287.31 g/mol
Synonyms	(4R)-4-Benzyl-3-[(1S,2S)-2-hydroxycyclopent-3-ene-1-carbonyl]-1,3-oxazolidin-2-one; (4R)-4-Benzyl-3-[(1S,2S)-2-hydroxy-3-cyclopenten-1-ylcarbonyl]-2-oxazolidinone; Evans Auxiliary Derivative; Chiral Oxazolidinone Auxiliary; (R)-4-Benzyl-3-((1S,2S)-2-hydroxy-3-cyclopenten-1-carbonyl)oxazolidin-2-one
EINECS	Contact for details

Quality Control

Our production of (4R)-3-[((1S,2S)-2-Hydroxy-3-Cyclopenten-1-Yl)Carbonyl]-4-(Phenylmethyl)-1,3-Oxazolidin-2-One adheres to stringent quality protocols suitable for research and pharmaceutical applications. Each batch is characterized and tested to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing comprehensive analytical results, including chiral purity by HPLC, are provided with every shipment. Our quality system supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.