Description

(+)-Albuterol Sulfate (1:1) is the active pharmaceutical ingredient (API) form of the widely used bronchodilator, specifically the dextrorotatory enantiomer of albuterol sulfate. This high-purity compound is critical for ensuring the efficacy and safety of inhalation therapies used to treat asthma, chronic obstructive pulmonary disease (COPD), and other respiratory conditions. Pharmaceutical manufacturers and advanced research institutions require this specific enantiomer for the development and production of metered-dose inhalers (MDIs), dry powder inhalers (DPIs), and nebulizer solutions.

Application

• Active Pharmaceutical Ingredient (API) in bronchodilator medications for asthma and COPD.
• Formulation of Metered-Dose Inhalers (MDIs) and Dry Powder Inhalers (DPIs).
• Production of nebulizer solutions for acute and chronic respiratory care.
• Reference standard for analytical method development and quality control in pharmaceutical labs.
• Research and development of new respiratory drug delivery systems and combination therapies.
• Precursor in synthetic chemistry for further pharmaceutical derivatization.

Basic Information

Item	Details
Product Name	(+)-Albuterol Sulfate (1:1)
CAS No.	324000-05-7
Molecular Formula	C26H44N2O10S
Molecular Weight	576.70 g/mol
Synonyms	(R)-Salbutamol Sulfate; Levalbuterol Sulfate; (R)-Albuterol Sulfate; (R)-4-[2-(tert-Butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol Sulfate; Xopenex® (brand name API); CAS 324000-05-7; (1:1) Salt of (R)-Albuterol and Sulfuric Acid
EINECS	Contact for details

Quality Control

Our (+)-Albuterol Sulfate (1:1) is manufactured and tested under a strict quality management system. Each batch is analyzed to meet stringent specifications for identity, purity, and enantiomeric excess, ensuring compliance with pharmaceutical-grade standards. Comprehensive testing includes chiral HPLC, residual solvent analysis, and microbiological limits. A Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Enantiomeric Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%
Microbiological Enumeration	Meets Ph. Eur. 2.6.12/2.6.13 criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.