Description

1-Boc-6-Chloroindole is a protected indole derivative of significant importance in synthetic organic chemistry. This compound serves as a versatile and critical building block for the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting various therapeutic areas, including oncology and CNS disorders.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the indole scaffold's bioactivity.
• Peptidomimetics & Bioconjugation: The Boc-protected amine and chloro-substituted indole ring make it valuable for creating peptide analogs and bioconjugation linkers.
• Material Science Research: Employed as a monomer or functional unit in the development of advanced organic electronic materials and polymers.
• Academic & Contract Research: Essential for methodological studies in heterocyclic and medicinal chemistry within academic and CRO (Contract Research Organization) settings.
• Custom Synthesis: Serves as a starting material for custom synthesis services to produce tailored, high-value chemical entities for specific client projects.

Basic Information

Product Name	1-Boc-6-Chloroindole
CAS No.	323580-68-3
Molecular Formula	C₁₃H₁₄ClNO₂
Molecular Weight	251.71 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-6-chloroindole; 6-Chloro-1H-indole-1-carboxylic acid, 1,1-dimethylethyl ester; tert-Butyl 6-chloro-1H-indole-1-carboxylate; 6-Chloro-1-Boc-indole; Boc-6-chloroindole; 1-Boc-6-chloro-1H-indole; N-Boc-6-chloroindole; 6-Chloroindole-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-6-Chloroindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.