Description

Carbamic Acid, (2,5-Dioxo-3-Pyrrolidinyl)-, 9H-Fluoren-9-Ylmethyl Ester (9Ci) is a specialized chemical building block, primarily used as an activated ester in peptide synthesis and other organic coupling reactions. Its core value lies in its role as a versatile reagent for introducing the Fmoc-protected carbamate group, which is crucial for constructing complex molecules with high precision. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and development.

Application

• Peptide Synthesis: As a key reagent for the Fmoc solid-phase peptide synthesis (SPPS) strategy, facilitating the controlled assembly of amino acids.
• Organic Intermediate: Serves as a protected amine synthon in the multi-step synthesis of complex organic molecules and active pharmaceutical ingredients (APIs).
• Bioconjugation: Used for the site-specific labeling and modification of biomolecules, such as proteins and oligonucleotides, for diagnostic and therapeutic applications.
• Polymer Chemistry: Employed in the synthesis of functionalized polymers and dendrimers that require precise amine-reactive handles.
• Chemical Biology Research: A valuable tool for probing biological systems and developing novel probes or inhibitors in academic and industrial R&D.
• Combinatorial Chemistry: Utilized in the generation of diverse compound libraries for high-throughput screening in drug discovery campaigns.

Basic Information

Product Name	Carbamic Acid, (2,5-Dioxo-3-Pyrrolidinyl)-, 9H-Fluoren-9-Ylmethyl Ester (9Ci)
CAS No.	323187-10-6
Molecular Formula	C19H15NO5
Molecular Weight	337.33 g/mol
Synonyms	Fmoc-OSu; N-(9-Fluorenylmethoxycarbonyloxy)succinimide; 9-Fluorenylmethyl N-succinimidyl carbonate; Fmoc-OSuc; Fmoc-O-Su; N-Fmoc-oxysuccinimide; N-[(9H-Fluoren-9-ylmethoxy)carbonyloxy]succinimide; N-(9-Fluorenylmethoxycarbonyl)oxysuccinimide
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (2,5-Dioxo-3-Pyrrolidinyl)-, 9H-Fluoren-9-Ylmethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific research or cGMP requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and performance. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	152 - 156 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.