Description

2-(1H-Indol-3-Yl)-2-Morpholinoacetonitrile is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines indole and morpholine pharmacophores linked by an acetonitrile group, making it a versatile precursor for pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel bioactive molecules and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop novel therapeutic agents.
• Agrochemical Synthesis: Serves as a building block for developing new crop protection agents and pesticides.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic & Institutional R&D: Utilized in universities and research institutes for methodological development and exploring new heterocyclic chemistry.
• Chemical Library Construction: A valuable component for creating diverse compound libraries for biological screening.

Basic Information

Product Name	2-(1H-Indol-3-Yl)-2-Morpholinoacetonitrile
CAS No.	321974-02-1
Molecular Formula	C₁₄H₁₅N₃O
Molecular Weight	241.29 g/mol
Synonyms	2-(1H-Indol-3-yl)-2-morpholin-4-ylacetonitrile; 2-(1H-Indol-3-yl)-2-(morpholin-4-yl)acetonitrile; 2-Morpholino-2-(1H-indol-3-yl)acetonitrile; 2-(1H-Indol-3-yl)-2-(4-morpholinyl)acetonitrile; 321974-02-1; 2-(1H-indol-3-yl)-2-morpholinoacetonitrile; Acetonitrile, 2-(1H-indol-3-yl)-2-(4-morpholinyl)-
EINECS	Contact for details

Quality Control

Our 2-(1H-Indol-3-Yl)-2-Morpholinoacetonitrile is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR, NMR), and impurity profile is provided with each shipment to guarantee reliable and reproducible performance in your synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.