Description

3-Thiazol-5-Yl-D-Alanine is a non-proteinogenic amino acid derivative featuring a thiazole heterocycle. This compound is of significant interest in pharmaceutical research and development, particularly as a key chiral building block for the synthesis of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, peptide mimetics, and drug discovery programs targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of potential drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a building block for creating compound libraries to explore structure-activity relationships (SAR) and identify new lead molecules.
• Peptide Mimetics Development: Incorporated into peptide analogs to enhance metabolic stability, bioavailability, and receptor binding affinity.
• Biochemical Tool Compound: Employed in biochemical assays and studies to investigate enzyme mechanisms or biological pathways involving amino acid metabolism.
• Agrochemical Research: Potential use as an intermediate in the development of novel crop protection agents and herbicides.

Basic Information

Product Name	3-Thiazol-5-Yl-D-Alanine
CAS No.	321885-21-6
Molecular Formula	C6H8N2O2S
Molecular Weight	172.21 g/mol
Synonyms	D-3-(5-Thiazolyl)alanine; (R)-2-Amino-3-(1,3-thiazol-5-yl)propanoic acid; 5-Thiazolyl-D-alanine; D-3-(Thiazol-5-yl)alanine; (R)-3-(1,3-Thiazol-5-yl)alanine; 3-(1,3-Thiazol-5-yl)-D-alanine; D-3-(1,3-Thiazol-5-yl)alanine; 3-(Thiazol-5-yl)-D-alanine
EINECS	Contact for details

Quality Control

Our 3-Thiazol-5-Yl-D-Alanine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile is supplied with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.