Description

4-(1H-Indol-6-Yl)-1-Methyl-Piperidin-4-Ol CAS NO 321744-84-7 is a high-purity, advanced pharmaceutical intermediate featuring a unique indole-piperidine hybrid structure. This compound is critical for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery pipelines. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates targeting serotonin and dopamine receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel CNS-active compounds.
• Preclinical Drug Development: Essential for producing gram to kilogram quantities of active pharmaceutical ingredients (APIs) for toxicology and early-phase clinical studies.
• Chemical Biology Probes: Utilized in the development of molecular probes to study neurological pathways and protein interactions.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) specializing in bespoke, complex organic molecules.

Basic Information

Product Name	4-(1H-Indol-6-Yl)-1-Methyl-Piperidin-4-Ol
CAS No.	321744-84-7
Molecular Formula	C14H18N2O
Molecular Weight	230.31 g/mol
Synonyms	1-Methyl-4-(1H-indol-6-yl)-4-piperidinol; 4-(1H-Indol-6-yl)-1-methylpiperidin-4-ol; 4-Piperidinol, 1-methyl-4-(1H-indol-6-yl)-; 4-Hydroxy-1-methyl-4-(1H-indol-6-yl)piperidine; 4-(6-Indolyl)-1-methyl-4-piperidinol
EINECS	Contact for details

Quality Control

Our production of 4-(1H-Indol-6-Yl)-1-Methyl-Piperidin-4-Ol adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, and our quality systems support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.