Description

n-(2-Oxotetrahydro-3-Thiophenyl)-3-(Trifluoromethyl)Benzenecarboxamide is a high-value, specialized organic intermediate featuring a unique heterocyclic thiophene scaffold combined with a trifluoromethylphenyl moiety. This compound is critical for its role in facilitating complex molecular transformations, particularly in the synthesis of advanced pharmaceutical ingredients and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the life sciences and fine chemical industries who require precise building blocks for creating novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for developing specialty polymers and organic electronic materials with tailored properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	n-(2-Oxotetrahydro-3-Thiophenyl)-3-(Trifluoromethyl)Benzenecarboxamide
CAS No.	321521-91-9
Molecular Formula	C13H12F3NO2S
Molecular Weight	303.30 g/mol
Synonyms	3-(Trifluoromethyl)-N-(2-oxotetrahydro-3-thienyl)benzamide; 3'-(Trifluoromethyl)-2-oxo-2,3-dihydrothiophene-3-carboxanilide; 3-(Trifluoromethyl)benzoic acid (2-oxotetrahydro-3-thienyl)amide; 2-Oxo-2,3-dihydrothiophene-3-carboxylic acid (3-trifluoromethylphenyl)amide; Amide, 3-(Trifluoromethyl)-N-(2-oxotetrahydro-3-thienyl)benzene-; Benzamide, 3-(trifluoromethyl)-N-(2-oxotetrahydro-3-thienyl)-
EINECS	Contact for details

Quality Control

Our n-(2-Oxotetrahydro-3-Thiophenyl)-3-(Trifluoromethyl)Benzenecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and other high-purity applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.